睡眠呼吸中止影響學(xué)習(xí)Morris水迷宮morris water maze

喝綠茶有助修復(fù)腦缺陷Morris水迷宮morris water maze

Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

美大鼠實(shí)驗(yàn)證實(shí)，間歇性低氧所致腦傷，綠茶多酚發(fā)揮改善功能。

Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

阻塞性睡眠呼吸中止（簡稱OSA）是常見的睡眠呼吸機(jī)能失調(diào)問題，許多報(bào)告早已指出，患者因?yàn)檠鯕獾拖拢瑢?dǎo)致氧化壓力（oxidativestress）升高，大腦掌管記憶與學(xué)習(xí)的部位也會受到影響。但是美國*新動物實(shí)驗(yàn)發(fā)現(xiàn)，多喝綠茶有助改善OSA導(dǎo)致的腦部缺陷。

Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

■抗氧化與**自由基

這項(xiàng)研究的秘密武器是「綠茶多酚」，研究團(tuán)隊(duì)看準(zhǔn)其抗氧化與**自由基的功能，找來106只大鼠做實(shí)驗(yàn)。在14天、每天12小時(shí)的供氧控制時(shí)間內(nèi)，大鼠氧氣供應(yīng)量受到限制，以便模擬阻塞性睡眠呼吸中止「間歇性低氧」（intermittenthypoxia）的情形Morris水迷宮morris watermaze。Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

研究團(tuán)隊(duì)做出「缺氧」大鼠后，將這些大鼠分成兩組，實(shí)驗(yàn)組喂食添加綠茶多酚的白開水，對照組則僅喂喝純白開水。Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

接下來，研究團(tuán)隊(duì)設(shè)計(jì)一套神經(jīng)科學(xué)實(shí)驗(yàn)中用到的墨利斯水迷宮（Morris watermaze）裝置，藉由大鼠尋找水中隱藏平臺的表現(xiàn)，測試牠們空間記憶的能力，以及大腦海馬回功能受損情形。Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

結(jié)果發(fā)現(xiàn)，喝綠茶的大鼠表現(xiàn)優(yōu)于喝白開水的大鼠。研究主持人、美國路易斯維爾大學(xué)（University ofLuisville）教授戴維．柯佐爾（David Gozal）表示，研究結(jié)果顯示「綠茶多酚有助于減少間歇性低氧導(dǎo)致的空間記憶學(xué)習(xí)缺損?！?/span>Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

■美專業(yè)期刊登載研究Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze

相關(guān)研究日前刊于5月號第2期《美國呼吸與重癥醫(yī)學(xué)期刊》（American Journal of Respiratory andCritical Care Medicine）?？谱魻柦ㄗh，未來進(jìn)一步實(shí)驗(yàn)證實(shí)后，綠茶多酚或可當(dāng)作阻塞性睡眠呼吸中止的介入**手段。Morris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water mazeMorris水迷宮morris water maze